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Available To Book Add Round-Trip Air from Lower 48 States for $495

Lower Mississippi River 5/15/2026-5/23/2026

Date: May 15-23, 2026
Starting Price: $5,995
Trip Length: 8 nights
Trip: New Orleans, Louisiana to Memphis, Tennessee
Cruise line: American Cruise Lines | American Serenade

Cruise the mighty Mississippi River from New Orleans to Memphis as you meander through stunning scenery and historical landscapes cruising 7 nights aboard American Cruise Lines’ American Serenade. Enjoy an ...

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