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Available To Book

Upper Mississippi River 9/12/2025-9/20/2025

Date: Sep 12-20, 2025
Starting Price: $5,545
Trip Length: 8 nights
Trip: St. Paul, Minnesota to St. Louis, Missouri (Alton, Illinois)
Cruise line: American Cruise Lines | American Serenade

Discover the beauty of the Upper Mississippi on this 8-night autumnal journey aboard American Cruise Lines’ American Serenade. Begin with a complimentary pre-cruise hotel stay in St. Paul, Minnesota, renowned ...

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